Diuretics help your body get rid of extra fluid by increasing how much urine the body makes. Diuretics can improve swelling and shortness of breath caused by fluid buildup. The most common diuretic is furosemide (Lasix).
Beta-blockers like metoprolol (Toprol) slow your heart rate and help your heart pump better.
Mineralocorticoid receptor antagonists (MRAs) such as spironolactone (Aldactone) help remove extra salt and water and protect the heart. These are generally started after delivery.
SGLT2 inhibitors, a newer type of heart failure medicine, such as dapagliflozin (Farxiga) or empagliflozin (Jardiance), help the heart work better and reduce fluid buildup. These are typically started after pregnancy and breastfeeding.
Blood thinners (anticoagulants) such as heparin or warfarin (Coumadin) may be used in severe cases to reduce the risk of blood clots. Your doctor will decide if this is needed based on your individual risk.
Bromocriptine stops the release of prolactin, which is an important hormone involved in lactation. Bromocriptine may help improve heart function in women with severe PPCM. The use of bromocriptine for PPCM is not routine and is currently being studied. Bromocriptine should be given with a blood thinner and should not be given to women who wish to breastfeed.
The REBIRTH study is a randomized clinical trial that will test whether bromocriptine can strengthen the heart in women diagnosed with PPCM. Visit the study website to learn who is eligible and to find a study site near you.
